Quote
Chemical structure of Tri-n-butyltin hydride | 688-73-3
CAS: 688-73-3
SKU: S2050
Tri-n-butyltin hydride | SKU: S2050
Synonyms: TBTH; Tri-n-butylstannane; Tributylstannane
Chemical structure of Tri-n-butyltin hydride | 688-73-3
Tri-n-butyltin Hydride (TBTH) is an organotin radical reductant that Sarchem Labs supplies as a liquid for pharmaceutical and fine-chemical manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
Request Quote — S2050

Specifications

Boiling Point80°C at 0.4 mmHg
Density1.082 g/mL at 25°C
Flash Point40°C
ColorColorless
Infrared SpectrumAuthentic
Assay Percent Range96% min. (GC)
PackagingGlass bottle
Linear Formula[CH3(CH2)3]3SnH
Formula Weight291.04
Physical FormLiquid
Chemical Name or MaterialTri-n-butyltin hydride
Molecular Weight291.06 g/mol
Merck Index15, 9783
Solubility InformationSolubility in water: reacts. Other solubilities: soluble in most organic solvents
Refractive Indexn20/D 1.473
Fieser01,1192; 02,424; 03,294; 04,518; 05,685; 06,604; 07,379; 08,497; 09,476; 10,411; 11,545; 12,516; 14,312; 15,325; 16,343; 17,351
Assay97% (matches Sarchem's existing 96% min. closely)
Viscosity1.5 mPa.s (20°C)
Specific Gravity1.08
CAS Number688-73-3
Storage Temperature2–8°C
NACRESNA.22
PubChem Substance ID24854056
UNSPSC Code12352103
MDL NumberMFCD00009416
Beilstein/REAXYS Number3587329
ApplicationsRadical dehalogenation and reductive-cleavage manufacturing processes

Applications

Radical dehalogenation and reductive-cleavage manufacturing processes
Intramolecular radical cyclization (pharmaceutical and fine-chemical synthesis)

Product Description

What is Tri-n-butyltin Hydride?

TBTH is one of the most widely used radical-chain reductants in organic synthesis, generating carbon radicals from alkyl/aryl halides via a tin-centered radical chain mechanism — a classic method for reductive dehalogenation and radical cyclization reactions.

Uses of Tri-n-butyltin Hydride

This reagent is used throughout pharmaceutical and fine-chemical manufacturing for radical dehalogenation, reductive cleavage of C-X bonds, and intramolecular radical cyclization reactions that construct ring systems difficult to access by ionic chemistry.

Safety Information

  • Signal Word: Danger | Hazard Statements: H226 (Flammable liquid and vapor), H301 (Toxic if swallowed), H312 (Harmful in contact with skin), H315 (Skin irritation), H319 (Eye irritation), H360FD (May damage fertility; may damage the unborn child), H372 (Causes damage to organs through prolonged or repeated exposure), H410 (Very toxic to aquatic life with long-lasting effects)
  • Hazard Classification: Acute Tox. 3 Oral, Acute Tox. 4 Dermal, Aquatic Acute 1, Aquatic Chronic 1, Eye Irrit. 2, Flam. Liq. 3, Repr. 1B, Skin Irrit. 2, STOT RE 1 (the most severe repeated-exposure organ-damage category)
  • PPE: Eyeshields, faceshields, gloves, type ABEK (EN14387) respirator filter — organotin compounds require strict exposure control
  • Storage Class: 3 – Flammable liquids | Flash Point: 40°C (closed cup)

Related Products

No related products found.

Other Products

FAQs: Tri-n-butyltin hydride

Mainly as a radical reductant for dehalogenation and radical cyclization reactions in pharmaceutical and fine-chemical manufacturing.

Yes, very seriously — it's classified Repr. 1B (may damage fertility or the unborn child) and STOT RE 1 (organ damage from repeated exposure), the most severe categories in both hazard classes. This compound requires strict occupational exposure controls and should not be handled without full awareness of these risks.

80°C at 0.4 mmHg (reduced pressure), an exact match to Sarchem's existing published data.

Yes, for every lot (SKU S2050).