Sodium starch glycolate is a pharmaceutical excipient often used as a disintegrant in tablet and capsule formulations. It helps tablets break down into tiny particles in the gastrointestinal system, resulting in quicker medication solubility and absorption. The pharmaceutical industry highly regards this chemical due to its efficacy and safety profile.
The sodium starch glycolate structure is built on a modified starch backbone. It is made up of cross-linked sodium carboxymethyl groups connected to starch polymers. This chemical alteration confers distinctive features, such as great water absorption and swelling capacity, making it an effective disintegrant. The cross-linking guarantees that the material does not entirely disintegrate but expands rapidly when in contact with water.
The chemical formula of sodium starch glycolate is often expressed as:
(C6H9O4Na)n
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