| Density | 2.16 g/mL at 25°C (lit.) |
| Linear Formula | NaHCO3 |
| Formula Weight | 84.01g/mol |
| Chemical Name or Material | Sodium Bicarbonate |
| UN Number | NONH for all modes of transport |
| Molecular Weight | 84.01 g/mol |
| SMILES String | [Na+].OC([O-])=O |
| Beilstein | 4153970 |
| CAS Number | 144-55-8 |
| EC Number | 205-633-8 |
| NACRES | NA.21 |
| PubChem Substance ID | 329824559 |
| UNSPSC Code | 12352302 |
| MDL Number | MFCD00003528 |
| InChI | 1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1 |
| InChI Key | UIIMBOGNXHQVGW-UHFFFAOYSA-M |
| pKa | 6.37 (1st), 10.25 (2nd, carbonic acid) |
| Beilstein Registry Number | 4153970 |
| Quality Level | 300 |
| Reference Grade | ACS reagent, ≥99.7% |
| Regulatory Suitability | Suitable for EPA 1621, EPA 300 |
Sodium Bicarbonate is the sodium salt of carbonic acid’s mono-protonated form, a mild alkaline compound that neutralizes acids in a gentle, well-controlled reaction rather than a harsh, fast one. That mildness — combined with excellent water solubility and a long track record of safety data — is why it’s one of the most broadly used buffering and neutralizing agents across pharmaceutical, food, and industrial chemistry.
In pharmaceutical formulation, sodium bicarbonate serves as an antacid active ingredient, a buffering agent in various dosage forms, and a key component of effervescent tablets. Food manufacturers use it as a leavening agent and pH regulator, while water-treatment and industrial-process operators rely on it for alkalinity adjustment and mild neutralization work — Sarchem’s ACS-reagent-grade material is suitable for EPA 1621 and EPA 300 analytical methods. It’s also a standard laboratory buffering reagent.
*Sodium bicarbonate carries no GHS hazard pictogram on Sigma’s reference listing — it is not classified as GHS-hazardous.*
