| Melting Point | 73–77 °C (marketplace reference; Sarchem's existing spec: 75 °C — consistent) |
| Color | White to yellow |
| Linear Formula | C5H12NCl |
| Formula Weight | 121.61 |
| percent purity | 97% |
| Physical Form | Solid (crystal-powder) |
| Chemical Name or Material | (R)-2-Methylpyrrolidine Hydrochloride |
| Molecular Weight | 121.61 g/mol |
| CAS Number | 135324-85-5 |
| Storage Temperature | Room temperature |
| MDL Number | MFCD06796610 |
| InChI | `1S/C5H11N.ClH/c1-5-3-2-4-6-5;/h5-6H,2-4H2,1H3;1H/t5-;/m1./s1` |
| InChI Key | JNEIFWYJFOEKIM-NUBCRITNSA-N |
| Salt Form | Hydrochloride (confirmed) |
| Applications | Chiral building block for asymmetric synthesis of pharmaceutical intermediates |
(R)-2-Methylpyrrolidine hydrochloride is the hydrochloride salt of (R)-2-methylpyrrolidine, a chiral five-membered nitrogen ring with a methyl group at the stereocenter carbon adjacent to the nitrogen. Salt formation with hydrochloric acid converts the volatile, air-sensitive free-base amine into a solid, shelf-stable crystalline powder — a common strategy for handling reactive chiral amines, since the salt form is far easier to weigh, store, and transport accurately than the liquid free base. Supplied by Sarchem Labs at 97% purity with a melting point around 73–77 °C, it delivers the same (R)-configured pyrrolidine chemistry as the free base once neutralized, in a more practical, storable form.
Like its free-base and (S)-enantiomer counterparts, (R)-2-methylpyrrolidine hydrochloride is used as a chiral building block in asymmetric synthesis, primarily for pharmaceutical intermediates where the (R)-configured pyrrolidine ring is specifically required for the target molecule’s activity. Its salt form makes it a convenient, stable starting material for synthesis routes that begin with a free-base liberation step (treating the salt with base to release the reactive amine in situ) before proceeding with further chemistry.
