CAS: 51019-43-3
SKU: S2957
(R)-(−)-O-Acetylmandelic acid | SKU: S2957
Synonyms: (−)-O-Acetyl-D-mandelic acid; (R)-(−)-α-Acetoxyphenylacetic acid
(R)-(−)-O-Acetylmandelic Acid is a chiral derivatizing agent that Sarchem Labs supplies as a white crystalline powder for analytical-chemistry and pharmaceutical research applications. Every lot ships with a Certificate of Analysis and Safety Data Sheet.

Specifications

Melting Point97–99°C
ColorWhite
Linear FormulaCH3CO2CH(C6H5)CO2H
Formula Weight194.19
Physical FormWhite crystalline powder
Chemical Name or Material(-)-O-Acetyl-D-mandelic Acid
Molecular Weight194.18 g/mol
Assay99%
CAS Number51019-43-3
NACRESNA.22
PubChem Substance ID24855256
UNSPSC Code12352108
MDL NumberMFCD00004249
Beilstein/REAXYS Number2694110
Optical Activity[α]20/D −152.4° (c=2 in acetone)
Optical Purityee: 98% (GLC)
ApplicationsChiral derivatizing agent for NMR determination of enantiomeric purity (α-deuterated carboxylic acids, alcohols, amines)

Applications

Chiral derivatizing agent for NMR determination of enantiomeric purity (α-deuterated carboxylic acids, alcohols, amines)
Pharmaceutical intermediate synthesis (precursor to chiral diamines and related building blocks)

Product Description

What is (R)-(−)-O-Acetylmandelic Acid?

This compound is a single-enantiomer chiral acid used as an NMR derivatizing agent — reacting with a target compound to form diastereomeric derivatives whose NMR signals become distinguishable, which is how researchers measure enantiomeric excess.

Uses of (R)-(−)-O-Acetylmandelic Acid

This reagent is used in analytical laboratories to determine the enantiomeric purity of chiral alcohols and amines by NMR, and as a precursor in pharmaceutical research toward chiral diamine intermediates.

Safety Information

  • Storage Class: 11 – Combustible Solids
  • PPE: Eyeshields, gloves, type N95 (US) respirator as standard good-handling practice

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FAQs: (R)-(−)-O-Acetylmandelic acid

Mainly as a chiral derivatizing agent for NMR-based enantiomeric-purity determination, and as a pharmaceutical research intermediate.

97–99°C, closely matching Sarchem's existing published value of 98°C.

Yes, for every lot (SKU S2957).