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Chemical structure of Pyrroloquinoline quinone | 72909-34-3
CAS: 72909-34-3
SKU: S2757
Pyrroloquinoline quinone | SKU: S2757
Synonyms: Methoxatin; PQQ; 4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid
Chemical structure of Pyrroloquinoline quinone | 72909-34-3
Pyrroloquinoline quinone (PQQ), CAS 72909-34-3, is a small, water-soluble ortho-quinone compound valued for its unusually stable redox-cycling ability. Its tricyclic core carries three carboxylic acid groups, letting it shuttle electrons through repeated oxidation-reduction cycles far more efficiently than many conventional antioxidant molecules, which is a large part of why it continues to draw interest from mitochondrial and cell-biology researchers. Sarchem Labs supplies this compound (SKU S2757) with a Certificate of Analysis and Safety Data Sheet issued for every batch. Commercially, PQQ is best known as a raw material for mitochondrial-support and antioxidant dietary supplement formulations, while in the laboratory it also serves as a reagent for redox biochemistry and bacterial enzyme cofactor studies
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Specifications

AppearanceRed to dark brown powder
Melting Point222–224°C
Molecular FormulaC14H6N2O8
Molecular Weight330.21 g/mol
SMILES StringN1C2=C(C3NC(C(O)=O)=CC=3C(=O)C2=O)C(C(O)=O)=CC=1C(O)=O
SolubilitySolubility
CAS Number72909-34-3
EC Number839-691-6
Recommended Storage Temperature2–8°C, protected from light and moisture
NACRESNA.79
UNSPSC Code12352106
MDL NumberMFCD00043125
PubChem CID1024
Beilstein/REAXYS Number3596812
FDA UNII47819QGH5L
InChIKeyMMXZSJMASHPLLR-UHFFFAOYSA-N
ApplicationsRaw material for mitochondrial-support and antioxidant dietary supplement/nutraceutical formulations

Applications

Raw material for mitochondrial-support and antioxidant dietary supplement/nutraceutical formulations
Redox cofactor research, including PQQ-dependent bacterial dehydrogenase studies
Antioxidant and oxidative-stress research in cell biology and biochemistry
Cognitive-health and healthy-aging formulation research
Reference material for HPLC analysis and QC testing of PQQ-containing products

Product Description

What is Pyrroloquinoline Quinone?

Pyrroloquinoline quinone (PQQ) is a naturally occurring, water-soluble ortho-quinone that functions as a redox cofactor and antioxidant, best known commercially as the active raw material in mitochondrial-support dietary supplements. First identified as a cofactor for bacterial dehydrogenase enzymes, PQQ carries three carboxylic acid groups around a fused ring system, letting it cycle repeatedly between oxidized and reduced states without breaking down.

Uses of Pyrroloquinoline Quinone

Biochemists use PQQ to study PQQ-dependent enzymes such as bacterial dehydrogenases, while cell biology labs use it in redox-signaling and oxidative-stress experiments. Formulators working on mitochondrial-support and cognitive-health products source it as a bulk raw material, often alongside CoQ10. Analytical labs also use it as an HPLC reference material for supplement QC testing.

Safety Information

  • GHS Pictogram: GHS07 (Warning)
  • Hazard Statements: H302, H315, H319, H332, H335
  • PPE: Chemical-resistant gloves, goggles/face shield, protective clothing, N95 respirator for dust
  • Storage Class: 11 – Combustible Solids | WGK: 3

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FAQs: Pyrroloquinoline quinone

72909-34-3, corresponding to the free acid form, C14H6N2O8, MW 330.21 g/mol — distinct from salt forms like the disodium salt.

Mainly as a mitochondrial-support supplement raw material and as a research reagent in redox biochemistry, enzyme cofactor studies, and HPLC reference work.

No — chemically distinct compounds often formulated together as complementary mitochondrial-support ingredients, not interchangeable.

It's a GHS "Warning"-level irritant (not severe) — standard PPE (gloves, eye protection, dust respirator) is recommended.

Yes, a Certificate of Analysis and SDS ship with every batch (SKU S2757).