CAS: 85371-64-8
SKU: S2751
Pinacidil Monohydrate | SKU: S2751

Specifications

AppearanceWhite to off-white solid / powder
Melting Point164 – 165 °C
pH of Liquid, Typical (10% soln)Not typically specified for solid research chemical (not applicable)
Specific Gravity ApproxNot routinely reported for powders
OdorCharacteristic (solid)
ColorWhite to off-white
Linear FormulaC₁₃H₁₉N · HO
IUPAC Name1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine; hydrate
Formula Weight~263.34 g/mol
percent purity≥ 98 %
Physical FormPowder / crystalline solid
Content / Assay Percent Range≥ 98 % (HPLC)

Applications

No Application Found

Product Description

Pinacidil Monohydrate is a research-grade chemical compound and the monohydrate form of pinacidil, a cyanoguanidine derivative known for its activity as a potassium channel opener. It is widely used in laboratory and pharmaceutical research to study ATP-sensitive potassium (KATP) channels, membrane hyperpolarisation, and related cellular and vascular mechanisms.

Safety Information

No Safety Information Found

Related Products

FAQs: Pinacidil Monohydrate

Pinacidil monohydrate is a potassium channel opener used primarily in research focused on cardiovascular health. It helps relax vascular smooth muscles, aiding in blood pressure regulation studies.

Pinacidil monohydrate is valued for its vasodilatory effects, making it essential in hypertension and cardiac pharmacology research. It helps investigate mechanisms of vascular tone and blood flow improvement.

Pinacidil monohydrate activates ATP-sensitive potassium channels in smooth muscle cells, leading to hyperpolarisation and vasodilation. This mechanism is key in understanding blood pressure modulation in experimental models.

Yes, pinacidil monohydrate is often used as a reference compound in the development of novel vasodilators. Its well-characterised mechanism provides a foundation for cardiovascular drug screening and testing.

Pinacidil monohydrate typically appears as a white to off-white powder, with good solubility in organic solvents. It remains stable under recommended storage conditions, ensuring consistent research results.