CAS: 50-65-7
SKU: S1789
Niclosamide | SKU: S1789
Synonyms: 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide; Niclosamide
Niclosamide is a chlorinated salicylanilide compound that Sarchem Labs supplies as a bulk research- and technical-grade chemical for pharmaceutical R&D, analytical, and formulation-development laboratories. It’s long been recognized as an anthelmintic active ingredient and has more recently drawn renewed research interest for antiviral, anticancer, and Wnt-signaling pathway studies. Sarchem Labs backs every lot with a Certificate of Analysis and Safety Data Sheet. This listing is a bulk research chemical, not a finished, regulatory-approved drug or pesticide product — any pharmaceutical or agricultural/molluscicidal end-use requires separately sourced, properly licensed material.

Specifications

Melting Point225–233°C
Vapor PressureVery low at room temp
ColorGreen-yellow
UN NumberUN3077
Molecular FormulaC13H8Cl2N2O4
Molecular Weight327.12 g/mol
Loss on Drying≤0.5%
Solubility InformationSoluble in methanol:acetone [1:1] (50mg/mL).
Sulfated Ash≤0.1%
Beilstein2820605
SolubilitySoluble in methanol:acetone (1:1), ~50 mg/mL
CAS Number50-65-7
PubChem CID4477
InChIKeyRJMUSRYZPJIFPJ-UHFFFAOYSA-N
Beilstein Registry Number2820605

Applications

Pharmaceutical R&D reference standard for anthelmintic/antiparasitic research
Antiviral and repurposing research (actively studied against several viral targets)
Anticancer and Wnt-signaling pathway research
Analytical method development and QC reference material
Molluscicide-mechanism research (historical/agricultural chemistry context)

Product Description

What is Niclosamide?

Niclosamide is a chlorinated salicylanilide — a benzamide built from a hydroxylated, chlorinated salicylic acid core linked to a chloronitroaniline ring. It’s on the World Health Organization’s Model List of Essential Medicines as an oral anthelmintic used against tapeworm infections, and it’s separately registered as a molluscicide for controlling snail vectors in schistosomiasis-endemic regions. Sarchem Labs supplies it as a research/bulk chemical, not as either finished product.

Uses of Niclosamide

Beyond its long-established anthelmintic and molluscicide history, niclosamide has become a widely studied research compound: it’s investigated as a repurposing candidate against several viral targets, as an inhibitor of Wnt/β-catenin signaling in cancer biology research, and as a reference compound in analytical method development. Pharmaceutical R&D teams use bulk-grade material like Sarchem’s for early-stage formulation, solubility, and stability studies before any regulated development pathway.

Safety Information

  • Signal Word: Warning
  • Hazard Statement: H400 (Very toxic to aquatic life)
  • Precautionary Statement: P273 (Avoid release to the environment)
  • PPE: Chemical-resistant gloves, safety goggles, dust mask/respirator when handling powder
  • Handling: Low vapor pressure at room temperature; avoid generating dust; prevent any release to waterways given its aquatic toxicity

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FAQs: Niclosamide

Niclosamide is used as a reference/research chemical in anthelmintic pharmacology, antiviral repurposing studies, Wnt-pathway cancer research, and analytical method development — not administered directly as a finished drug from this listing.

No — Sarchem supplies niclosamide as a bulk research/technical-grade chemical. The approved anthelmintic drug and the EPA-registered molluscicide are separate, regulated finished products requiring licensed sourcing.

Yes — it's classified H400 (very toxic to aquatic life), so release to drains, soil, or waterways must be avoided and waste disposed of per local environmental regulations.

C13H8Cl2N2O4, with a molecular weight of approximately 327.12 g/mol.

Yes, for every lot (SKU S1789), so buyers can confirm identity and purity before use in a research or formulation program.