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Chemical structure of N-Methyl-1-naphthalenemethylamine hydrochloride | 65473-13-4
CAS: 65473-13-4
SKU: S1751
N-Methyl-1-naphthalenemethylamine hydrochloride | SKU: S1751
Synonyms: Terbinafine Related Compound A; N-Methyl-1-(naphthalen-1-yl)methanamine hydrochloride
Chemical structure of N-Methyl-1-naphthalenemethylamine hydrochloride | 65473-13-4
N-Methyl-1-naphthalenemethylamine Hydrochloride is a naphthylmethylamine that Sarchem Labs supplies as a crystalline solid for pharmaceutical manufacturing — it’s the key intermediate in the synthesis of terbinafine, a widely used antifungal drug. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
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Specifications

Melting Point191–193°C
ColorWhite-Yellow
Linear FormulaC10H7CH2NHCH3 · HCl
Formula Weight207.70
Physical FormCrystals
Chemical Name or MaterialN-Methyl-1-naphthylmethylamine Hydrochloride
Molecular Weight207.70 g/mol
Assay98%
CAS Number65473-13-4
NACRESNA.22
PubChem Substance ID24855873
UNSPSC Code12352100
MDL NumberMFCD00012555
ApplicationsAntifungal drug manufacturing — this compound is the confirmed key synthetic intermediate for terbinafine (brand name Lamisil), a widely prescribed antifungal active pharmaceutical ingredient

Applications

Antifungal drug manufacturing — this compound is the confirmed key synthetic intermediate for terbinafine (brand name Lamisil), a widely prescribed antifungal active pharmaceutical ingredient
Analytical chemistry (reagent for isocyanate determination in air via UV/fluorescence detection)

Product Description

What is N-Methyl-1-naphthalenemethylamine Hydrochloride?

This compound is a secondary amine built on a naphthalenemethyl scaffold. Its primary significance is as the confirmed key building block in the commercial synthesis of terbinafine, where it’s carried through the later synthetic steps to build the final antifungal drug structure.

Uses of N-Methyl-1-naphthalenemethylamine Hydrochloride

This compound is manufactured at scale as a key intermediate in terbinafine antifungal drug production, and is separately used as an analytical reagent for detecting isocyanates in air via UV or fluorescence methods.

Safety Information

  • Storage Class: 11 – Combustible Solids
  • PPE: Dust mask type N95 (US), eyeshields, gloves

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FAQs: N-Methyl-1-naphthalenemethylamine hydrochloride

Its primary use is as the key intermediate in terbinafine (antifungal drug) manufacturing.

This is a bulk research/manufacturing intermediate, not a finished, approved drug product — it is one synthetic step removed from the active pharmaceutical ingredient terbinafine.

Yes, for every lot (SKU S1751).