Quote
Chemical structure of Lidocaine HCL | 6108-05-0
CAS: 6108-05-0
SKU: S3381
Lidocaine HCl Monohydrate | SKU: S3381
Synonyms: 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride monohydrate; Lignocaine hydrochloride monohydrate; Xylocaine hydrochloride monohydrate (brand reference only)
Chemical structure of Lidocaine HCL | 6108-05-0
Lidocaine HCl Monohydrate is a white crystalline solid that Sarchem Labs supplies as a bulk research- and API-grade chemical for pharmaceutical R&D and analytical laboratories. It’s the active ingredient in the widely used local anesthetic marketed as Xylocaine, working as a sodium-channel blocker. Sarchem Labs backs every lot with a Certificate of Analysis and Safety Data Sheet. This listing is a bulk research/API-grade chemical, not a finished, FDA-approved drug product.
Request Quote — S3381

Specifications

Melting Point75–79°C
ColorWhite
Formula Weight288.82 (270.80 Anhydrous)
Physical FormCrystalline powder
Chemical Name or MaterialLidocaine hydrochloride monohydrate
UN NumberUN2811
Molecular Weight288.81 g/mol (270.80 anhydrous)
SMILES StringCl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C
Merck Index14, 5482
Solubility InformationSoluble in water (50mg/ml),chloroform,ethanol,and benzene. Insoluble in diethyl ether.
SolubilityWater 50 mg/mL; soluble in chloroform, ethanol, benzene; insoluble in diethyl ether
CAS Number6108-05-0
EC Number200-803-8
Empirical FormulaC14H22N2O · HCl · H2O
NACRESNA.77
PubChem Substance ID24277718
UNSPSC Code12352200
MDL NumberMFCD00150329
InChI1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
InChI KeyYECIFGHRMFEPJK-UHFFFAOYSA-N
Quality Level200
ApplicationsPharmaceutical R&D reference standard (local anesthetic/sodium-channel blocker research)

Applications

Pharmaceutical R&D reference standard (local anesthetic/sodium-channel blocker research)
Analytical method development (UPLC, FT-IR reference standard work)
Ion-channel research (Nav1.7 dose-response studies)
Process chemistry and formulation-development studies

Product Description

What is Lidocaine HCl Monohydrate?

Lidocaine HCl Monohydrate is the hydrochloride salt of lidocaine, a synthetic aminoamide compound that blocks voltage-gated sodium channels to interrupt nerve-signal transmission. That sodium-channel-blocking action is the mechanistic basis for its widespread use as a local anesthetic, and it also gives it class IB antiarrhythmic activity.

Uses of Lidocaine HCl Monohydrate

Sarchem’s research/API-grade material supports pharmaceutical R&D work: reference-standard use in UPLC and FT-IR method development, ion-channel research studying sodium voltage-gated channel (Nav1.7) responses, and formulation-development studies for controlled-release drug delivery systems. It is not supplied as, and should not be used as, a finished medication.

Safety Information

  • Signal Word: Danger | Hazard Statement: H301 (Toxic if swallowed)
  • Storage Class: 6.1C – Combustible, toxic/chronic-effect materials
  • PPE: Dust mask (type N95), eyeshields, faceshields, gloves

Related Products

No related products found.

Other Products

FAQs: Lidocaine HCl Monohydrate

As a reference standard for analytical method development (UPLC, FT-IR), ion-channel research, and pharmaceutical formulation-development studies.

Chemically the same active compound, but Sarchem supplies it as a bulk research/API-grade chemical, not the finished, FDA-approved Xylocaine drug product, which requires separately sourced, regulatory-approved material.

It's classified Danger, toxic if swallowed (H301); standard PPE including a dust mask and full eye/face protection is recommended.

C14H22N2O·HCl·H2O, molecular weight 288.81 g/mol (270.80 g/mol anhydrous basis).

Yes, for every lot (SKU S3381).