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CAS: 5256-76-8
SKU: S2428
L-Arginine alpha-ketoglutarate (2:1) | SKU: S2428
Synonyms:Di-Arginine oxoglutarate; 2-Oxopentanedioic acid compound with (2S)-2-amino-5-{[amino(imino)methyl]amino}pentanoic acid (1:2)
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L-Arginine Alpha-Ketoglutarate (2:1), commonly known as AAKG, is a salt formed by combining two molecules of the amino acid L-arginine with one molecule of alpha-ketoglutarate, supplied by Sarchem Labs for sports-nutrition and dietary-supplement formulation research. It’s one of the most widely recognized nitric-oxide-precursor ingredients in the pre-workout supplement category. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
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Specifications

AppearanceN/A
Content of ZincN/A
Boiling PointN / A
Melting PointN/A
Vapor PressureN/A
% Volatile by WeightN/A
Solubility in WaterN/A
DensityN/A
pH of Liquid, Typical (10% soln)N/A
Specific Gravity ApproxN/A
OdorN/A
pHN/A
Flash PointN/A
Ignition temperatureN/A
Lower exposure limitN/A
Upper exposure limitN/A
Linear FormulaC17H34O9N8
Physical FormSolid
Molecular Weight494.51 g/mol
CAS Number5256-76-8
Storage Temperature2–8°C, inert atmosphere
MDL NumberMFCD00673325
InChI1S/2C6H14N4O2.C5H6O5/c2*7-4(5(11)12)2-1-3-10-6(8)9;6-3(5(9)10)1-2-4(7)8/h2*4H,1-3,7H2,(H,11,12)(H4,8,9,10);1-2H2,(H,7,8)(H,9,10)/t2*4-;/m00./s1
InChI KeyNCRWNFFIHNRODM-SCGRZTRASA-N

Applications

Sports-nutrition and pre-workout supplement formulation raw material
Nitric-oxide precursor research (vasodilation/blood-flow studies)
Amino-acid and metabolic research

Product Description

What is L-Arginine Alpha-Ketoglutarate?

L-Arginine Alpha-Ketoglutarate is a salt combining two equivalents of L-arginine, a semi-essential amino acid and precursor to nitric oxide, with one equivalent of alpha-ketoglutarate, a key intermediate in the citric acid (Krebs) cycle. Pairing these two metabolically active molecules is intended to support both nitric-oxide-related vasodilation pathways and cellular energy metabolism.

Uses of L-Arginine Alpha-Ketoglutarate

AAKG’s dominant commercial use is as a raw material in sports-nutrition and pre-workout supplement formulations, where it’s valued for its role as a nitric-oxide precursor supporting vasodilation and blood-flow research. It’s also used in broader amino-acid and metabolic research studying arginine and citric-acid-cycle pathways.

Safety Information

  • Signal Word: Warning | Hazard Statements: H315 (Skin irritation), H319 (Serious eye irritation), H335 (May cause respiratory irritation)
  • PPE: Eyeshields, gloves, dust mask

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FAQs: L-Arginine alpha-ketoglutarate (2:1)

Mainly as a sports-nutrition and pre-workout supplement raw material valued for its nitric-oxide precursor activity, and in broader amino-acid/metabolic research.

It refers to two molecules of L-arginine combined with one molecule of alpha-ketoglutarate in the salt structure.

C17H34O9N8, molecular weight 494.51 g/mol.

It carries mild irritant classifications (H315/H319/H335); standard PPE (gloves, eye protection, dust mask) is recommended.

Yes, for every lot (SKU S2428).