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Chemical structure of Glucuronolactone | 32449-92-6
CAS: 32449-92-6
SKU: S3187
Glucuronolactone | SKU: S3187
Synonyms: D-Glucurono-3,6-lactone; Glucurone
Chemical structure of Glucuronolactone | 32449-92-6
Glucuronolactone is the intramolecular lactone (cyclic ester) form of D-glucuronic acid, supplied by Sarchem Labs as a white crystalline solid for nutraceutical formulation and biochemical research. It’s a natural human metabolite involved in carbohydrate metabolism and is widely recognized as a common ingredient in energy-drink and supplement formulations. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
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Specifications

Melting Point170–175°C
pH3.5 (10% H2O soln.)
ColorWhite
Formula Weight176.12
Physical FormSolid
Chemical Name or MaterialD-Glucurono-6,3-lactone
Molecular Weight176.12 g/mol
Specific Rotation+17.0 to +19.0° (c=8, water)
CAS Number32449-92-6
Storage Temperature2–30°C
Empirical FormulaC6H8O6
NACRESNA.22
UNSPSC Code12352115
MDL NumberMFCD00135622
InChIKeyUYUXSRADSPPKRZ-SKNVOMKLSA-N
Quality Level200
Reference Assay≥97.0% (acidimetric)
ApplicationsNutraceutical and energy-supplement formulation raw material

Applications

Nutraceutical and energy-supplement formulation raw material
Biochemical research into glucuronic acid metabolism and detoxification pathways
Cosmetic-ingredient formulation research
Analytical reference material for glucuronidation-pathway studies

Product Description

What is Glucuronolactone?

Glucuronolactone is formed when D-glucuronic acid cyclizes into a stable, five-membered lactone (internal ester) ring. It’s a naturally occurring human metabolite, produced as an intermediate in the glucuronic acid pathway of carbohydrate metabolism, which also plays a role in the body’s glucuronidation detoxification processes.

Uses of Glucuronolactone

Glucuronolactone’s best-known commercial use is as a formulation ingredient in energy drinks and dietary supplements, often paired with caffeine and taurine. In research settings, it’s used to study glucuronic acid metabolism and the glucuronidation pathway that the liver uses to process and eliminate various compounds.

Safety Information

*This reference listing carries no GHS hazard pictogram or hazard statement — it is not classified as GHS-hazardous.*

  • Storage Class: 11 – Combustible Solids
  • PPE: Eyeshields, gloves, dust mask as standard good-handling practice

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FAQs: Glucuronolactone

Most commonly as a formulation ingredient in energy drinks and dietary supplements, and as a research compound for studying glucuronic acid metabolism.

Yes — it's a natural human metabolite formed as part of the glucuronic acid pathway, which is also involved in the body's detoxification (glucuronidation) processes.

32449-92-6, C6H8O6, molecular weight 176.12 g/mol.

No — glucuronolactone is the cyclic lactone (internal ester) form of D-glucuronic acid; the two are closely related and interconvertible but structurally distinct.

Yes, for every lot (SKU S3187).