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3-Ethynylaniline
CAS: 54060-30-9
SKU: S1541
3-Ethynylaniline | SKU: S1541
Synonyms: none listed beyond the systematic name
3-Ethynylaniline
3-Ethynylaniline is a terminal-alkyne aniline that Sarchem Labs supplies as a liquid for pharmaceutical and advanced-materials manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
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Specifications

Boiling Point120°C
ColorBrown
Linear FormulaHC≡CC6H4NH2
Formula Weight117.15
Physical FormClear Liquid at 20°C
Chemical Name or Material3-Ethynylaniline
Molecular Weight117.15 g/mol
Assay≥98%
CAS Number54060-30-9
Storage Temperature2–8°C
EC Number258-944-6
NACRESNA.22
PubChem Substance ID24873187
MDL NumberMFCD00014779

Applications

Cancer drug manufacturing — used as a reagent in the multi-step synthesis of erlotinib hydrochloride (Tarceva), an FDA-approved lung/pancreatic cancer drug
High-performance polymer manufacturing — building block for acetylene-functional benzoxazine resins used in aviation, electronics, automotive, and energy applications
Click chemistry building block (terminal alkyne)

Product Description

What is 3-Ethynylaniline?

This compound combines a terminal alkyne with an aniline (aromatic amine), giving two independently useful reactive handles: the alkyne for click chemistry/cross-coupling and the amine for amide or imine formation — both exploited across pharmaceutical and advanced-materials manufacturing.

Uses of 3-Ethynylaniline

This compound is used as a key reagent in the multi-step manufacturing of erlotinib hydrochloride, an approved targeted cancer therapy, and as a monomer building block for high-performance acetylene-functional benzoxazine resins used in aviation, electronics, and automotive manufacturing.

Safety Information

  • Signal Word: Warning | Hazard Statements: H226 (Flammable liquid and vapor), H315 (Skin irritation), H319 (Eye irritation), H335 (Respiratory irritation)
  • Hazard Classification: Eye Irrit. 2, Flam. Liq. 3, Skin Irrit. 2, STOT SE 3
  • PPE: Eyeshields, gloves, type ABEK (EN14387) respirator filter
  • Storage Class: 3 – Flammable liquids | Flash Point: 59°C (closed cup)

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FAQs: 3-Ethynylaniline

Mainly as a reagent in erlotinib (cancer drug) manufacturing, and as a monomer in high-performance benzoxazine resin manufacturing for aerospace and electronics applications.

Yes, for every lot (SKU S1541).