CAS: 304-55-2
SKU: S2355
Dimercaptosuccinic acid | SKU: S2355
Synonyms: Succimer, meso-2,3-dimercaptosuccinic acid, DMSA, DIM-SA
Dimercaptosuccinic acid (DMSA), CAS 304-55-2, is a dithiol-bearing dicarboxylic acid best known as a heavy-metal chelating agent, supplied by Sarchem Labs as a white crystalline powder for research and industrial chelation-chemistry applications. Its two thiol (–SH) groups bind strongly to soft heavy-metal ions such as lead, cadmium, and zinc, which is the chemical basis for its widespread use in metal-chelation research and metal-removal technologies. Sarchem Labs backs every lot with a Certificate of Analysis and Safety Data Sheet. It is used in research involving heavy-metal remediation, nanoparticle surface chemistry, and metal-cluster synthesis.

Specifications

Melting Point196–198 °C (dec., lit.)
ColorWhite
Linear FormulaHO2CCH(SH)CH(SH)CO2H
Formula Weight182.21
Physical FormCrystal-powder
Chemical Name or Materialmeso-2,3-Dimercaptosuccinic Acid
Molecular Weight182.21–182.22 g/mol
SMILES String`OC(=O)[C@@H](S)[C@@H](S)C(O)=O`
Beilstein1725150
Assay~98%
CAS Number304-55-2
Storage Temperature−20 °C
EC Number206-155-2
Key Functional GroupsThiol
NACRESNA.22
PubChem Substance ID57654130
UNSPSC Code12352100
MDL NumberMFCD00064799
Quality Segment200
InChI`1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+`
InChI KeyACTRVOBWPAIOHC-XIXRPRMCSA-N

Applications

Chelating agent for removing toxic heavy-metal contaminants (Zn(II), Cd(II), Pb(II)) from aqueous solutions, including surface-monolayer applications on micromotor platforms
Reducing and stabilizing agent in the synthesis of monolayer-protected gold nanoclusters
Surface-functionalization reagent for terminal carboxylation of oleylamine-coated Fe3O4 nanoparticles, supporting targeted drug-delivery system development
Reference/research chemical for heavy-metal chelation chemistry studies

Product Description

What is Dimercaptosuccinic Acid (DMSA)?

Dimercaptosuccinic acid, commonly abbreviated DMSA and also known by its pharmaceutical name succimer, is a small dicarboxylic acid carrying two adjacent thiol groups on its central carbon backbone. Those two thiol groups are the molecule’s defining feature: sulfur is a “soft” donor atom that binds especially strongly to soft heavy-metal ions like lead, cadmium, mercury, and zinc, which is why DMSA is one of the most recognized chelating agents in both chemistry and medicine. Supplied by Sarchem Labs as a white, ~98%-assay crystalline powder, it should be stored at −20 °C to preserve its reactive thiol groups from oxidation.

Uses of Dimercaptosuccinic Acid (DMSA)

DMSA’s core chemistry — two thiol groups that bind heavy metals strongly — underlies its use as a chelating agent in environmental and materials research, including forming monolayers on micromotor surfaces to actively capture and remove toxic zinc, cadmium, and lead contaminants from polluted water. The same thiol chemistry makes it a useful reducing and stabilizing agent in the synthesis of monolayer-protected gold nanoclusters, where its sulfur groups anchor onto the gold surface. DMSA’s carboxylic acid groups also provide a route for further surface functionalization, as seen in its use to install terminal carboxyl groups on oleylamine-coated iron oxide (Fe3O4) nanoparticles in the development of targeted drug-delivery systems.

any medical or clinical use would require a properly licensed, pharmaceutical-grade source and is outside the scope of this listing.

Safety Information

  •       Storage Class: 11 – Combustible Solids
  •       Water Hazard Class (WGK): 2
  •       Recommended PPE: Eye shields, gloves, and a type N95 (US) respirator
  •       Storage Temperature: −20 °C
  •       Flash Point: Not applicable

No GHS pictograms, signal word, or H-/P-code statements were present in the reference data reviewed — consult the current SDS for complete GHS hazard classification before use.

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FAQs: Dimercaptosuccinic acid

DMSA is used primarily as a heavy-metal chelating agent in research and materials chemistry, including removing lead, cadmium, and zinc contaminants from water, stabilizing gold nanoclusters, and functionalizing nanoparticle surfaces.

Its two thiol (–SH) groups are strong "soft" donor sites that form stable bonds with soft heavy-metal ions like lead, cadmium, and mercury, which is the chemical basis for its chelating ability.

Chemically, yes — DMSA (succimer) is an FDA-approved oral medication for lead and heavy-metal poisoning, but Sarchem's product is supplied as a research/industrial-grade chemical, not a pharmaceutical-grade product suitable for medical use.

It should be stored at −20 °C, since its reactive thiol groups are susceptible to oxidation over time, which would reduce its metal-chelating effectiveness.

Every lot ships with a Certificate of Analysis and Safety Data Sheet so customers can confirm identity, assay (~98%), and handling requirements before use.