Chemical structure of 4,6-Dichloro-5-nitropyrimidine | 4316-93-2
SKU: S1386

4,6-Dichloro-5-nitropyrimidine | 4316-93-2 | Sarchem Labs

SKU: S1386

Description

20312

4,6-Dichloro-5-nitropyrimidine (CAS 4316-93-2) is a halogenated pyrimidine intermediate (≥98% purity) used in organic synthesis. It’s mainly applied in pharmaceutical and agrochemical research as a building block for active compounds and crop protection agents. This solid chemical has a molecular weight of ~194 g/mol and requires careful handling due to irritant properties.

Synonym:pyrimidine, 4,6-dichloro-5-nitro, 4,6-dichloro-5-nitro-pyrimidine, 4,6-dichloro-5-nitro-pyridine, pubchem7078, acmc-1an8c, 4-23-00-00899 beilstein handbook reference, ksc495i5h, 4,6-dichloro-5-nitroprimidine, 4,6 dichloro-5-nitropyrimidine, 5-nitro 4,6-dichloropyrimidine

SPECIFICATION

AppearanceWhite to off-white to pale yellow / pale brown crystalline solid
Melting Point100 – 103 °C (literature)
pH of Liquid, Typical (10% soln)Not typically measured for this solid intermediate
Specific Gravity ApproxApprox. 1.7–1.74 g/cm³
OdorSlight chemical / typical organic nitro compound odor
ColorWhite to off-white to pale yellow / pale brown
Linear FormulaCHClNO
IUPAC Name4,6-Dichloro-5-nitropyrimidine
Formula Weight193.98 g/mol
percent purity≥ 98 % (HPLC / GC)
Physical FormCrystalline solid / powder
Chemical Name or Material4,6-Dichloro-5-nitropyrimidine
Beilstein162029
Content / Assay Percent Range≥ 98 % (HPLC / GC)

Safety Information

Classification of the substance or mixture

GHS Label elements, including precautionary statements

Yes

Hazards not otherwise classified (HNOC) or not covered by GHS

Yes

GHS Classification in accordance with 29 CFR 1910 (OSHA HCS). For the full text of the H-Statements mentioned in this Section, see Section 16.

Yes

Signal word :

Warning

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FAQs: 4,6-Dichloro-5-nitropyrimidine

4,6-Dichloro-5-nitropyrimidine is a halogenated heterocyclic compound used as an intermediate in pharmaceutical and agrochemical synthesis. Its reactive chlorine and nitro groups make it valuable for creating complex organic molecules.

The compound contains two chlorine atoms and one nitro group on a pyrimidine ring. These substituents enhance its electrophilicity, enabling selective nucleophilic substitution reactions important in advanced synthetic pathways.

4,6-Dichloro-5-nitropyrimidine is usually produced by chlorination of nitropyrimidine derivatives under controlled conditions. The process is optimized to achieve high yields and purity for subsequent industrial or research applications.

It is widely used as a building block for pharmaceuticals, herbicides, and specialty chemicals. Its functional groups make it an essential intermediate for synthesizing biologically active heterocyclic compounds.

Yes, due to its chemical reactivity, handling requires protective gloves, goggles, and good ventilation. Avoid inhalation or skin contact, and follow standard laboratory safety protocols during storage and use.