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4-Chloro-3,5-dinitrobenzotrifluorideb | 393-75-9
CAS: 393-75-9
SKU: S1262
4-Chloro-3,5-dinitrobenzotrifluorideb | SKU: S1262
Synonyms: CDNT; DNT-Cl
4-Chloro-3,5-dinitrobenzotrifluorideb | 393-75-9
4-Chloro-3,5-dinitrobenzotrifluoride (CDNT) is a highly activated aromatic building block that Sarchem Labs supplies as a solid for agrochemical intermediate manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
Request Quote — S1262

Specifications

Melting Point50–55°C
ColorYellow
Linear FormulaClC6H2(NO2)2CF3
Quantity25g
Formula Weight270.55
percent purity≥98.0% (GC)
Physical FormSolid
Chemical Name or Material4-Chloro-3,5-dinitrobenzotrifluoride
UN Number2811
Molecular Weight270.55 g/mol
Assay98%
SolubilityWater: insoluble
CAS Number393-75-9
EC Number206-889-3
NACRESNA.22
PubChem Substance ID24851818
MDL NumberMFCD00007068
Beilstein/REAXYS Number1220937
ApplicationsAgrochemical intermediate manufacturing (activated aryl chloride for nucleophilic aromatic substitution)

Applications

Agrochemical intermediate manufacturing (activated aryl chloride for nucleophilic aromatic substitution)
Analytical-chemistry derivatization reagent (HPLC determination of amikacin and amino acids)

Product Description

What is 4-Chloro-3,5-dinitrobenzotrifluoride?

This compound combines a chlorine leaving group with two nitro groups and a trifluoromethyl group, all strongly electron-withdrawing — making the chlorine highly activated toward nucleophilic aromatic substitution, a reactivity profile widely exploited in agrochemical manufacturing.

Uses of 4-Chloro-3,5-dinitrobenzotrifluoride

This compound is used as a key building block in agrochemical intermediate manufacturing via nucleophilic aromatic substitution of its activated chlorine, and as a derivatization reagent in HPLC-based analytical methods.

Safety Information

  • Signal Word: Danger | Hazard Statements: H302 (Harmful if swallowed), H310 (Fatal in contact with skin), H315 (Skin irritation), H319 (Eye irritation)
  • Hazard Classification: Acute Tox. 2 Dermal, Acute Tox. 4 Oral, Eye Irrit. 2, Skin Irrit. 2
  • PPE: Eyeshields, faceshields, gloves, type P2 (EN 143) respirator cartridges — Acute Tox. 2 Dermal is a severe classification requiring strict dermal-exposure control
  • Storage Class: 6.1A | Flash Point: 126°C (closed cup)

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FAQs: 4-Chloro-3,5-dinitrobenzotrifluorideb

Mainly as an activated building block for agrochemical intermediate manufacturing via nucleophilic aromatic substitution.

Yes, seriously — it's classified Acute Tox. 2 Dermal (fatal in contact with skin); strict dermal-exposure protection is required.

Yes, for every lot (SKU S1262).