CAS: 112704-79-7
SKU: S2869
4-Bromo-2-fluorobenzoic acid | SKU: S2869
Synonyms: none listed beyond the systematic name
4-Bromo-2-fluorobenzoic Acid is a halogenated benzoic acid that Sarchem Labs supplies as a solid for pharmaceutical intermediate manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.

Specifications

AppearanceN/A
Content of ZincN/A
Boiling PointN / A
Melting Point211–215°C
Vapor PressureN/A
% Volatile by WeightN/A
Solubility in WaterN/A
DensityN/A
pH of Liquid, Typical (10% soln)N/A
Specific Gravity ApproxN/A
OdorN/A
pHN/A
Flash PointN/A
Ignition temperatureN/A
Lower exposure limitN/A
Upper exposure limitN/A
ColorWhite-Yellow
Linear FormulaBrC6H3(F)COOH
Formula Weight219.01
Physical FormCrystal-powder at 20°C
Chemical Name or Material4-Bromo-2-fluorobenzoic Acid
Molecular Weight219.01 g/mol
Assay97%
CAS Number112704-79-7
NACRESNA.22
PubChem Substance ID24864450
UNSPSC Code12352100
MDL NumberMFCD00143263
ApplicationsOncology drug manufacturing — this compound has been identified as a related compound/impurity reference relevant to enzalutamide (Xtandi), an approved prostate cancer drug

Applications

Oncology drug manufacturing — this compound has been identified as a related compound/impurity reference relevant to enzalutamide (Xtandi), an approved prostate cancer drug
Biaryl pharmaceutical intermediate manufacturing (palladium-mediated coupling with aryl boronic acids)

Product Description

What is 4-Bromo-2-fluorobenzoic Acid?

This compound is a benzoic acid substituted with both bromine and fluorine. The bromine provides a handle for palladium-mediated cross-coupling to build biaryl structures, a common step in constructing complex pharmaceutical intermediates.

Uses of 4-Bromo-2-fluorobenzoic Acid

This compound is used in pharmaceutical manufacturing as a building block for biaryl intermediates via palladium-catalyzed coupling with aryl boronic acids, and is specifically documented as relevant to enzalutamide-related oncology drug chemistry.

Safety Information

  • Storage Class: 11 – Combustible Solids
  • PPE: Eyeshields, gloves, type N95 (US) respirator

Related Products

FAQs: 4-Bromo-2-fluorobenzoic acid

Mainly as a biaryl-building-block intermediate in pharmaceutical manufacturing, including enzalutamide-related oncology drug chemistry.

Yes, for every lot (SKU S2869).