CAS: 927-74-2
SKU: S1236
3-Butyn-1-ol | SKU: S1236
Synonyms: 3-Butynol
3-Butyn-1-ol is a terminal alkyne alcohol that Sarchem Labs supplies as a clear liquid for pharmaceutical and heterocyclic-chemistry manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.

Specifications

Boiling Point128.9°C
Melting Point−63.6°C
Density0.926 g/mL at 25°C (lit.)
ColorYellow
Linear FormulaHC≡CCH2CH2OH
Formula Weight70.09
percent purity≥97.0% (GC)
Physical FormLiquid
Chemical Name or Material3-Butyn-1-ol
UN Number1987
Molecular Weight70.09 g/mol
Refractive Indexn20/D 1.441 (lit.)
Assay97%
CAS Number927-74-2
EC Number213-161-9
NACRESNA.22
PubChem Substance ID24847980
UNSPSC Code12352100
MDL NumberMFCD00002955
Beilstein/REAXYS Number773710

Applications

Pharmaceutical intermediate manufacturing (terminal-alkyne building block for click chemistry, cross-coupling, and heterocycle synthesis)
Synthon for oxygen-containing heterocycle and protected amino-acid ester manufacturing

Product Description

What is 3-Butyn-1-ol?

This compound combines a terminal alkyne with a primary alcohol two carbons away, giving it two distinct reactive handles — the alkyne for coupling/cycloaddition chemistry and the alcohol for esterification or further functionalization.

Uses of 3-Butyn-1-ol

This compound is used as a building block in pharmaceutical manufacturing, serving as a synthon for oxygen-containing heterocycles and protected amino-acid ester intermediates, and as a terminal-alkyne partner in palladium-catalyzed coupling reactions.

Safety Information

  • Signal Word: Warning | Hazard Statements: H226 (Flammable liquid and vapor), H315 (Skin irritation), H319 (Eye irritation), H335 (Respiratory irritation)
  • Hazard Classification: Eye Irrit. 2, Flam. Liq. 3, Skin Irrit. 2, STOT SE 3
  • PPE: Eyeshields, faceshields, gloves, type ABEK (EN14387) respirator filter
  • Storage Class: 3 – Flammable liquids | Flash Point: 36°C (closed cup)

Related Products

FAQs: 3-Butyn-1-ol

Mainly as a terminal-alkyne building block in pharmaceutical manufacturing (click chemistry, cross-coupling, heterocycle synthesis).

Yes — it's classified Warning, flammable, and irritating to eyes/skin/respiratory tract; use a fume hood and standard flammable-liquid precautions.

Yes, for every lot (SKU S1236).