Buy 7-Azaindole | Sarchem Labs

Name: 7-Azaindole
Brand: Sarchem Labs
SKU: S1865

CAS: 271-63-6

SKU: S1865

7-Azaindole (1H-Pyrrolo[2,3-b]pyridine) | SKU: S1865

Synonyms: 1H-Pyrrolo(2,3-b)pyridine

7-Azaindole is a nitrogen-substituted indole (bicyclic heterocycle) that Sarchem Labs supplies as a solid for pharmaceutical manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.

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Specifications

Boiling Point	270°C
Melting Point	105–107°C
Color	Undesignated
Formula Weight	118.14
Physical Form	Solid
Chemical Name or Material	1H-Pyrrolo[2,3-b]pyridine
Molecular Weight	118.14 g/mol
Assay	98%
CAS Number	271-63-6
EC Number	205-981-0
Empirical Formula	C7H6N2
NACRES	NA.22
PubChem Substance ID	24891472
MDL Number	MFCD00005606
Applications	Kinase-inhibitor drug manufacturing — 7-azaindole is a validated fragment-based drug-discovery scaffold, identified as a protein kinase B (Akt) inhibitor core structure used in oncology drug development

Applications

Kinase-inhibitor drug manufacturing — 7-azaindole is a validated fragment-based drug-discovery scaffold, identified as a protein kinase B (Akt) inhibitor core structure used in oncology drug development

Pharmaceutical building block for pyrrolopyridine-containing drug candidates

Product Description

What is 7-Azaindole?

7-Azaindole is an indole ring system with one carbon replaced by nitrogen, giving it an additional hydrogen-bond-accepting site compared to plain indole. That extra nitrogen is a key feature exploited in kinase-inhibitor drug design, where it forms favorable interactions with the kinase hinge region.

Uses of 7-Azaindole

This heterocyclic building block is used extensively in pharmaceutical manufacturing as a kinase-inhibitor scaffold — fragment-based screening identified 7-azaindole as a protein kinase B (Akt) inhibitor core, and it’s a recurring building block across many kinase-targeted drug-candidate synthesis programs.