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1,8-Octanediol
CAS: 629-41-4
SKU: S1807
1,8-Octanediol | SKU: S1807
synonyms: Octamethylene glycol; 1,8-Dihydroxyoctane; Octane-1,8-diol; 1,8-Octylene glycol
1,8-Octanediol
1,8-Octanediol, also known as octamethylene glycol, is a linear aliphatic diol with a hydroxyl group at each end of an eight-carbon chain, HO(CH2)8OH. It is a white crystalline solid with a reference assay of 98%, a literature melting range of 57–61 °C and a boiling point of 172 °C at 20 mmHg. The long, flexible, even-numbered carbon chain makes it a valuable monomer. In polyesters and polyurethanes, 1,8-octanediol introduces soft, hydrophobic segments that lower glass-transition temperature, improve flexibility and impact resistance and reduce water uptake. It is also the diol component of the biodegradable elastomer poly(1,8-octanediol citrate), widely studied in tissue-engineering research, and it serves as a starting material for diacrylates, dibromides and other α,ω-difunctional building blocks. Sarchem Labs offers 1,8-octanediol (SKU S1807) for polymer producers, coatings and adhesives formulators, and research laboratories. Each lot ships with a Certificate of Analysis and Safety Data Sheet, and the product can be quoted in laboratory through bulk quantities.
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Specifications

AppearanceN/A
Content of ZincN/A
Boiling Point172°C at 20 mmHg (lit.)
Melting Point57–61°C (lit.)
Vapor PressureN/A
% Volatile by WeightN/A
Solubility in WaterN/A
DensityN/A
pH of Liquid, Typical (10% soln)N/A
Specific Gravity ApproxN/A
OdorN/A
pHN/A
Flash Point120°C (248°F), closed cup
Ignition temperatureN/A
Lower exposure limitN/A
Upper exposure limitN/A
Linear FormulaHO(CH2)8OH
Formula Weight146.23
Physical FormCrystal-Powder at 20°C
Chemical Name or Material1,8-Octanediol
Molecular Weight146.23 g/mol
SMILES StringOCCCCCCCCO
Assay98%
CAS Number629-41-4
EC Number211-090-8
Empirical FormulaC8H18O2
NACRESNA.22
PubChem Substance ID24897977
UNSPSC Code12352100
MDL NumberMFCD00002989
InChI1S/C8H18O2/c9-7-5-3-1-2-4-6-8-10/h9-10H,1-8H2
InChI KeyOEIJHBUUFURJLI-UHFFFAOYSA-N
Beilstein/REAXYS Number1633499
Quality Level100
Functional GroupsHydroxyl
FormCrystal-powder at 20°C

Applications

No Application Found
Polyurethanes: serves as a chain extender and soft-segment diol in thermoplastic polyurethanes, elastomers, coatings and adhesives.
Biodegradable elastomers: undergoes polycondensation with citric acid to form poly(1,8-octanediol citrate) (POC), a crosslinked biodegradable bioelastomer that can be blended with additives and is used in biomedical-materials research.
Macromers and crosslinkers: Fischer esterification with dicarboxylic acids forms diol-based macromers, and esterification with acrylic or methacrylic acid gives 1,8-octanediol diacrylate or dimethacrylate for UV-curing and dental resins.
Lubricants and plasticisers: the diol esters are used as synthetic lubricant base stocks and plasticiser components.
Fine-chemical intermediate: converted to 1,8-dibromooctane, 1,8-octanediamine and α,ω-functional spacers for pharmaceuticals, liquid crystals and molecular electronics.

Product Description

What is 1,8-Octanediol?

1,8-Octanediol is a straight-chain C8 alkane substituted with a primary hydroxyl group at each terminal carbon. Its formula is C8H18O2 (written HO(CH2)8OH) and its molecular weight is 146.23 g/mol. Both hydroxyl groups are primary and equally reactive, which gives clean, symmetrical condensation chemistry with acids, isocyanates and acid chlorides.

The reference grade is 98% pure, melts at 57–61 °C and boils at 172 °C under 20 mmHg. The compound has a closed-cup flash point of 120 °C and is classified as a combustible solid with no GHS hazard pictogram in the reference listing. Its long hydrocarbon chain gives it limited water solubility compared with shorter diols, and good solubility in alcohols and many organic solvents.

Uses of 1,8-Octanediol

In the polymer industry, 1,8-octanediol is used where a flexible, hydrophobic C8 spacer is desired. Compared with shorter diols such as 1,4-butanediol it gives softer, lower-melting polyesters and polyurethanes with better hydrolytic stability; compared with longer chains it remains easy to handle and react. Coatings and adhesive formulators also use its (meth)acrylate esters as flexible reactive diluents.

In biomedical materials research, 1,8-octanediol and citric acid react without catalyst to form POC, a soft, elastic, biocompatible polymer that has been used to prepare scaffolds, vascular grafts and drug-delivery matrices in academic work. In organic synthesis, it is a convenient α,ω-difunctional starting point.

Buying and Handling Considerations

For polymer-grade work, request the lot’s assay, moisture and acid-value data; water and monofunctional impurities act as chain terminators and limit molecular weight in step-growth polymerisation. Store in a tightly closed container in a cool, dry place, away from strong oxidisers and acid chlorides. The material is a crystalline solid that can cake on standing; gently warm the closed container above its melting point, or break up the lumps, before weighing.

Safety Information

Based on Sigma-Aldrich’s verified listing (O3303).

  • GHS Classification: no pictogram, signal word or hazard statement is assigned in the reference listing
  • Storage Class: 11 – Combustible solids | WGK: 3 | Flash Point: 120°C (248°F), closed cup
  • PPE: Type N95 (US) dust mask, eyeshields, gloves

Avoid dust, contact with eyes and prolonged skin contact, and keep away from ignition sources. Handle with ordinary good industrial hygiene.

Related Products

No related products found.

Other Products

FAQs: 1,8-Octanediol

It is used as a monomer and chain extender in polyesters and polyurethanes, as the diol in the biodegradable elastomer poly(1,8-octanediol citrate), as a precursor to diacrylates and other α,ω-difunctional compounds, and as an intermediate in fine-chemical and materials synthesis.

The formula is C8H18O2 (HO(CH2)8OH) and the molecular weight is 146.23 g/mol. The CAS number is 629-41-4.

The literature melting range is 57–61 °C and the boiling point is 172 °C at 20 mmHg for the 98% reference grade. The closed-cup flash point is 120 °C.

1,8-Octanediol has hydroxyl groups at both ends of the chain (CAS 629-41-4) and is used as a polymer monomer. 1,2-Octanediol (caprylyl glycol, CAS 1117-86-8) has adjacent hydroxyls and is mainly a cosmetic humectant and preservative booster.

It is a crosslinked biodegradable polyester made by condensing 1,8-octanediol with citric acid, without added catalyst. It is an elastomer studied in tissue engineering, wound-healing and drug-delivery research.

The reference listing assigns no GHS classification. It is a combustible solid (storage class 11), so use dust protection, avoid ignition sources, and follow normal hygiene practices.

Yes. SKU S1807 is supplied with a lot-specific Certificate of Analysis and Safety Data Sheet, and Sarchem Labs provides quotes from laboratory packs to bulk volumes.