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Chemical structure of 1,6-Dibromo-1,6-dideoxy-D-mannitol | 488-41-5
CAS: 488-41-5
SKU: S2284
1,6-Dibromo-1,6-dideoxy-D-mannitol | SKU: S2284
Synonyms: Mitobronitol; Dibromomannitol; DBM; Myelobromol
Chemical structure of 1,6-Dibromo-1,6-dideoxy-D-mannitol | 488-41-5
1,6-Dibromo-1,6-dideoxy-D-mannitol, known by its pharmaceutical name Mitobronitol (or dibromomannitol, DBM), is a brominated sugar alcohol that Sarchem Labs can supply as a bulk research-grade chemical for oncology research. It’s the active ingredient in a historical alkylating-agent chemotherapy treatment for chronic myeloid leukemia. This listing is a bulk research chemical, not a finished drug product.
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Specifications

AppearanceN/A
Content of ZincN/A
Boiling PointN / A
Melting PointN/A
Vapor PressureN/A
% Volatile by WeightN/A
Solubility in WaterN/A
DensityN/A
pH of Liquid, Typical (10% soln)N/A
Specific Gravity ApproxN/A
OdorN/A
pHN/A
Flash PointN/A
Ignition temperatureN/A
Lower exposure limitN/A
Upper exposure limitN/A
Physical FormSolid (colorless crystals per secondary sources)
Molecular Weight307.97 g/mol
CAS Number488-41-5
Empirical FormulaC6H12Br2O4

Applications

Oncology research (alkylating-agent mechanism studies)
Historical chronic myeloid leukemia (CML) treatment research reference
Carbohydrate-chemistry alkylating-agent research

Product Description

What is Mitobronitol?

Mitobronitol is formed by replacing the two terminal hydroxyl groups of D-mannitol with bromine atoms, creating a bifunctional alkylating agent. Historically, it was used as an alternative to busulfan for myelosuppression therapy in chronic myeloid leukemia, with some clinical data suggesting a reduced-complication profile relative to busulfan in certain bone-marrow-transplant contexts.

Uses of Mitobronitol

Sarchem’s research-grade material supports oncology and pharmacology research into alkylating-agent mechanisms and historical CML treatment approaches. It is not supplied as, and should not be used as, a finished medication.

Safety Information

*Given this compound’s history as a cytotoxic chemotherapy alkylating agent, treat with the same handling rigor as other antineoplastic research compounds — request your own current SDS documentation, as detailed GHS classification could not be independently confirmed via secondary sources.*

  • PPE: Full chemical-resistant protective equipment appropriate for a cytotoxic/alkylating research compound

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FAQs: 1,6-Dibromo-1,6-dideoxy-D-mannitol

As a research compound for studying alkylating-agent chemotherapy mechanisms and historical chronic myeloid leukemia treatment approaches.

No — Sarchem supplies it as a bulk research chemical, not a finished, approved drug product; any therapeutic use requires separately sourced, regulatory-approved material.

C6H12Br2O4, molecular weight 307.97 g/mol.

Please confirm with your team, given the elevated hazard profile expected for a cytotoxic alkylating agent — ensure current SDS documentation is readily available.