Quote
available for purchase from Sarchem laboratories. please contact us for pricing and lead-time 1-Naphthoyl chloride | 879-18-5
CAS: 879-18-5
SKU: S1783
1-Naphthoyl chloride | SKU: S1783
Synonyms: 1-Naphthalenecarbonyl chloride; 1-Naphthoic acid chloride; alpha-Naphthoyl chloride
available for purchase from Sarchem laboratories. please contact us for pricing and lead-time 1-Naphthoyl chloride | 879-18-5
1-Naphthoyl Chloride (CAS 879-18-5) is an aromatic acyl chloride built on a naphthalene backbone, supplied by Sarchem Labs for research, analytical, and industrial synthesis. Like other acyl chlorides, it hydrolyzes readily to release HCl gas, making anhydrous handling essential. Sarchem ships every lot with a COA and SDS. It’s used mainly as an acylating agent installing the 1-naphthoyl group onto alcohols and amines, and as a UV/fluorescence derivatization reagent in HPLC analysis.
Request Quote — S1783

Specifications

Boiling Point190°C at 35 mmHg (lit.)
Melting Point16–19°C (lit.)
Density1.265 g/mL at 25°C
Flash Point>110°C
ColorYellow
Formula Weight190.63
Physical FormClear Liquid at 20°C
Chemical Name or Material1-Naphthoyl Chloride
UN NumberUN3265
Molecular FormulaC11H7ClO
Molecular Weight190.63 g/mol
SMILES StringClC(=O)c1cccc2ccccc12
CAS Number879-18-5
EC Number212-903-9
Recommended Storage Temperature2–8°C under inert gas, tightly sealed
NACRESNA.22
UNSPSC Code12352100
MDL NumberMFCD00004002
PubChem CID70146
Beilstein/REAXYS Number775785
InChIKeyNSNPSJGHTQIXDO-UHFFFAOYSA-N
Color / Physical Form (Sarchem spec, kept)Yellow / Clear liquid at 20°C
PubChem SID24855045

Applications

Acylating agent for naphthoate esters and naphthamides
Pharmaceutical/agrochemical intermediate synthesis
HPLC derivatization reagent (fatty alcohols, alcohol ethoxylates, mycotoxins)
Arndt-Eistert homologation and naphthoyl-indole synthesis
Precursor for naphthalene dyes, pigments, polymer additives

Product Description

What is 1-Naphthoyl Chloride?

1-Naphthoyl chloride is the acid chloride of 1-naphthoic acid — a pale yellow liquid that acylates alcohols and amines to form naphthalene esters and amides. The peri-hydrogen near its carbonyl chloride makes it notably more reactive than simpler aroyl chlorides like benzoyl chloride, which also means it reacts vigorously with atmospheric moisture.

Uses of 1-Naphthoyl Chloride

Used to build naphthalene-containing pharmaceutical and agrochemical scaffolds via standard acylation, and to derivatize weakly-detectable analytes (fatty alcohols, mycotoxins) into naphthalene-tagged compounds for HPLC UV/fluorescence detection. Also used in Arndt-Eistert homologation and naphthoyl-indole synthesis.

Safety Information

  • Signal Word: Danger | GHS Pictogram: GHS05 (Corrosion)
  • Hazard Statement: H314 — Causes severe skin burns and eye damage
  • Transport: UN3265, Class 8, PG II | Storage Class: 8A | WGK: 3
  • PPE: Chemical-resistant gloves, goggles/face shield, acid-gas respirator cartridges

Related Products

No related products found.

Other Products

FAQs: 1-Naphthoyl chloride

As an acylating agent for naphthalene esters/amides in pharma/agrochemical synthesis, and as an HPLC derivatization reagent.

Yes — GHS Skin Corrosion Category 1B (Danger, H314); causes severe skin burns and eye damage.

879-18-5, C11H7ClO, MW 190.63 g/mol — do not confuse with 2-Naphthoyl chloride (CAS 2243-83-6).

Sealed, under inert atmosphere, ideally refrigerated 2–8°C, away from moisture.

Yes — hydrolyzes to 1-naphthoic acid and HCl gas; handle under anhydrous conditions.