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chemical structure of 1-(3-Chlorophenyl)piperazine hydrochloride | 65369-76-8
CAS: 65369-76-8
SKU: S1298
1-(3-Chlorophenyl)piperazine hydrochloride | SKU: S1298
Synonyms: m-CPP
chemical structure of 1-(3-Chlorophenyl)piperazine hydrochloride | 65369-76-8
1-(3-Chlorophenyl)piperazine Hydrochloride (mCPP) is an arylpiperazine that Sarchem Labs supplies as a powder for pharmacological research and pharmaceutical intermediate manufacturing. Every lot ships with a Certificate of Analysis and Safety Data Sheet.
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Specifications

Melting Point210–214°C
ColorBrown
Formula Weight196.68 (Anhydrous)
Physical FormSolid
Chemical Name or Material1-(3-Chlorophenyl)piperazine hydrochloride
Molecular Weight196.68 g/mol
Assay99%
SolubilityMethanol: soluble
CAS Number65369-76-8
EC Number265-718-0
Empirical FormulaC10H13ClN2 · xHCl
NACRESNA.22
PubChem Substance ID24847652
UNSPSC Code12352100
MDL NumberMFCD00039032
ApplicationsPharmaceutical intermediate/reference-standard use — mCPP is the major identified metabolite of the antidepressants trazodone and nefazodone, making it relevant to pharmacokinetic and drug-metabolism research

Applications

Pharmaceutical intermediate/reference-standard use — mCPP is the major identified metabolite of the antidepressants trazodone and nefazodone, making it relevant to pharmacokinetic and drug-metabolism research
Serotonin (5-HT) receptor pharmacology research — mCPP is a widely used non-selective 5-HT receptor agonist tool compound in neuroscience research

Product Description

What is mCPP?

mCPP is an arylpiperazine that acts as a non-selective agonist across multiple serotonin receptor subtypes, making it a standard pharmacological tool compound for probing serotonergic signaling. It’s also the principal active metabolite formed when the body metabolizes trazodone or nefazodone.

Uses of mCPP Hydrochloride

This compound is used in serotonin-receptor pharmacology research, in drug-metabolism/pharmacokinetic studies of trazodone and nefazodone, and as a reference standard in forensic and analytical toxicology (GC-MS/LC-MS methods for detecting designer piperazines).

Safety Information

  • Signal Word: Warning | Hazard Statements: H302 (Harmful if swallowed), H315 (Skin irritation), H319 (Eye irritation), H335 (Respiratory irritation)
  • Hazard Classification: Acute Tox. 4 Oral, Eye Irrit. 2, Skin Irrit. 2, STOT SE 3
  • PPE: Dust mask type N95 (US), eyeshields, faceshields, gloves
  • Storage Class: 11 – Combustible Solids

Sold strictly as a bulk research chemical / pharmaceutical intermediate — not for human consumption or unauthorized use.

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FAQs: 1-(3-Chlorophenyl)piperazine hydrochloride

Mainly as a serotonin-receptor pharmacology research tool and as a reference standard for trazodone/nefazodone metabolite studies.

No — unlike some other arylpiperazines, mCPP is not scheduled under US federal law and is sold openly by major suppliers, though it does have a documented recreational-misuse history and carries narcotics-law restrictions in some other countries (e.g., Germany).

210–214°C (decomposition)

Yes, for every lot (SKU S1298).