Chemical structure of 1,1,-Bis (4-Chlorophenyl)-2,2,2-Trichloroethane 4,4'-DTT | 50-29-3
SKU: S2424

2,4-Diamino 6-Chloropyrimidine | 156-83-2 | Sarchem Labs

SKU: S2424

Description

67432

Synonym : 4-chloro-2,6-diaminopyrimidine, 2,4-diamino-6-chloropyrimidine, 2,6-diamino-4-chloropyrimidine, 6-chloro-2,4-diaminopyrimidine, 6-chloro-pyrimidine-2,4-diamine, 2,4-pyrimidinediamine, 6-chloro, 4-chloro-2,6-diamino pyrimidine, 2-amino-6-chloro-4-pyrimidinylamine, caap, minoxidil impurity b

Color White-Yellow
Melting Point 198°C
Formula Weight 144.56
Physical Form Crystal-Powder at 20°C
Chemical Name or Material 6-Chloro-2,4-diaminopyrimidine

2,4-Diamino-6-chloropyrimidine is an important organic molecule frequently used as a building block in pharmacological and agricultural applications. Its structure is a pyrimidine ring with amino groups at locations 2 and 4 and a chlorine atom at position 6. This novel structure gives the compound remarkable chemical characteristics, making it a useful intermediary in producing a variety of physiologically active compounds.

2,4-Diamino-6-Chloropyrimidine Synthesis

The 2,4-diamino-6-chloropyrimidine synthesis involves several events, including nucleophilic substitutions and amination processes. One typical way is to chlorinate 2,4-diaminopyrimidine, which entails introducing a chlorine atom at the 6-position of the pyrimidine ring by halogenation. Another strategy employs precursor chemicals, such as chloropyrimidine derivatives, which are changed by adding amino groups at positions 2 and 4. This chemical sequence provides for the easy manufacture of 2,4-diamino-6-chloropyrimidine, frequently with high purity.

Because of its reactivity, 2,4-diamino-6-chloropyrimidine acts as a precursor in various chemical processes, aiding the Synthesis of novel molecules in pharmaceutical research.

Melting Point and Boiling Point

Melting Point: The melting point of 2,4-diamino-6-chloropyrimidine is normally between 199–202°C. This comparatively high melting point is compatible with its crystalline structure, shared by many aromatic heterocycles.

Boiling Point: Although the precise boiling point is rarely mentioned due to the compound’s probable breakdown at high temperatures, 2,4-diamino-6-chloropyrimidine is usually considered stable under normal laboratory settings, with decomposition happening before boiling.

 

SPECIFICATION

AppearanceN/A
Content of ZincN/A
Boiling PointN / A
Melting PointN/A
Vapor PressureN/A
% Volatile by WeightN/A
Solubility in WaterN/A
DensityN/A
pH of Liquid, Typical (10% soln)N/A
Specific Gravity ApproxN/A
OdorN/A
pHN/A
Flash PointN/A
Ignition temperatureN/A
Lower exposure limitN/A
Upper exposure limitN/A

Safety Information

Classification of the substance or mixture

GHS Label elements, including precautionary statements

Hazards not otherwise classified (HNOC) or not covered by GHS

 

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2,4-Diamino 6-Chloropyrimidine | 156-83-2 FAQs

Chlorination and amination are commonly used processes in the production of 2,4-diamine-6-chloropyrimidine. Specific reaction variables, such as temperature and catalyst selection, are optimised to achieve high yield and purity in industrial or research settings.

To work with 2,4-diamino-6-chloropyrimidine, gloves, goggles, and sufficient ventilation are required. Because of its possible chemical reactivity and health risks upon direct exposure, it must be synthesised or used in processes according to safety guidelines.

Reaction temperature, solvent selection, and catalyst quality determine the efficiency of 2,4-diamino-6-chloropyrimidine synthesis. These variables influence yield, reaction time, and the purity of the final product.

2,4-Diamino-6-chloropyrimidine is distinguished by its two amino groups and a chloro substituent, which increases its reactivity. This enables specific alterations essential for complicated chemical and medicinal production.

2,4-Diamino-6-Chloropyrimidine is widely utilised in the pharmaceutical, agrochemical, and research sectors. 2,4-Diamino-6-Chloropyrimidine synthesis is critical for creating medicines, insecticides, and other chemical products that need precise molecular arrangements.